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Kristine Yaffe Group

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Welcome to the Kristine Yaffe Group!
Our mission is to investigate the risk and resilience factors for cognitive aging and dementia, especially to identify opportunities for prevention.
Our Director
Learn about Dr. Kristine Yaffe, and her novel work in the epidemiology of dementia and cognitive aging.
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What We Do
Our team is dedicated to protecting cognitive health across the lifespan. We pioneer population-based research identifying modifiable risk factors for dementia and cognitive aging, including their biological connections, to develop prevention strategies.
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Latest Breakthrough
Published in The Lancet, our new research shows that midlife plasma biomarkers (Aβ42, Aβ40, and p-tau217) are associated with accelerated cognitive decline. These findings indicate that blood tests may offer a means of early detection for potential AD.
View Publication

News

September 15, 2026

Dr. Yaffe recognized by NAM as the recipient of the 2026 Rhoda and Bernard Sarnat International Prize in Mental Health

An eldery woman touches forehead with a caretaker, who is a middle-aged lady.
July 01, 2026

Dr. Yaffe shares the latest on modifiable risk factors for dementia prevention

May 29, 2026

Higher levels of AD biomarkers linked to cognitive performance at midlife

February 10, 2026

Yaffe Group highlights sensory impairments as risk factors for AD/ADRD in supplemental issue

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Our Network

We emphasize a multidisciplinary perspective that bridges psychiatry, neurology, and epidemiology. This framework is further strengthened by our dynamic network of scientific partners at UCSF, including the Center for Population Brain Healthexternal site (opens in a new window), the UCSF Memory and Aging Center, the Weill Institute for Neurosciencesexternal site (opens in a new window), the Alzheimer's Disease Research Centerexternal site (opens in a new window), the Pepper Centerexternal site (opens in a new window), and the Global Brain Health Instituteexternal site (opens in a new window).

To learn more, please explore our Research and Publications pages.

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